Australian (ASX) Stock Market Forum

SPL - Starpharma Holdings

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Knobby22 said:
Let's look at their early testing which is now in phase two trials. they gave it to a guy who had had 30 treatments of chemo and was somehow still alive and very resitant to treatment. It worked.
They have found also that the dose is low, below predicted before the drug worked. This is a big deal.
Trials are taking place in the UK. I sense is a real buzz with some of the big pharmas.
Click to expand...

Looks like some of this detail is highlighted, along with other detail in the latest ASX release Knobby. If I read this right the patients seem to be suffering long term chronic conditions as a 'prerequisite' for selection. Phase 2 is underway and with continued great news will hopefully get a lot more big pharma interest and maybe see some good growth.
Well, I'm hoping anyways.
https://www.asx.com.au/asxpdf/20191210/pdf/44cfvf8bnfs5vm.pdf
 
jbocker said:
Looks like some of this detail is highlighted, along with other detail in the latest ASX release Knobby. If I read this right the patients seem to be suffering long term chronic conditions as a 'prerequisite' for selection. Phase 2 is underway and with continued great news will hopefully get a lot more big pharma interest and maybe see some good growth.
Well, I'm hoping anyways.
https://www.asx.com.au/asxpdf/20191210/pdf/44cfvf8bnfs5vm.pdf
Click to expand...

You are quite right. It's a last resort thing at present to be considered for phase 2.

    • Recruitment into the phase 2 part of the trial is now underway with two new trial sites being added – Imperial College London and Velindre Cancer Centre in Cardiff

I may pick this company again for next years comp. (though it let me down this year).
If the sales figures for Vivagel are good and USA grants permission to sell it we should get a decent rise.Unfortunately we have to wait for the phase 2 trials to complete and then recruit for the phase 3 trials. A lot of investors will wait. I may increase my reasonably large holding later next year.

What I am pleased about is how eager the hospitals are to trial this. This suggests to me the effect of Big Pharma. Much easier to improve an existing drug owned by the big boys than go through the process of competing with them. I am also hoping they manage to speed up the process by fast tracking recruitment. I know with little Mesoblast it is all so long and painful to recruit.

With the DEP drug, the completed animal testing in September, Phase 1 now, phase 2 being recruited quickly I hope.
 
Why I am picking in 2020 competition. I have it as my top pick.
Vivagel gets approval in USA by the FDA and this opens up another big market.
The DEP programs are progressing well with Phase 2 trials getting some great results in cancer treatment. I would think that more of these trials will prove positive and hopefully ground-breaking. Big Pharma is getting involved and I would trust more to come.
 
Well I only just noticed that this was announced today...
SPL7013 shows significant activity against SARS-CoV-2 (coronavirus)
It is an interesting read. There are already approvals for products that contain the antiviral dendrimer SPL7013 so if they prove it up...could get exciting.
I think it was announced after market close so it may cause a bit of excitement tomorrow? :woot: (Now that I have said that,.. it probably wont :rolleyes: I guess a lot have already been banging this drum).
https://www.asx.com.au/asxpdf/20200415/pdf/44gzbt0tc135t6.pdf
 
Starpharma product shows significant activity against coronavirus
William McInnes
Today AFR

Starpharma says its antiviral dendrimer, SPL7013, has been shown to have significant activity against the SARS-CoV-2 virus which causes COVID-19.

The company said the dendrimer inhibited the infection of cells with the virus and the finding was validated by replicate testing against a positive control compound.

The company said it was evaluating product concepts and formulation options for SPL7013 which may have potential applications in the prevention and management of COVID-19.

The dendrimer is already approved as an active component in two existing products which already have regulatory approval in Europe, Canada, Japan, Australia and South East Asia, meaning it should be possible to fast track the development path.

"Following the emergence of the coronavirus pandemic in February, Starpharma instigated testing of SPL7013 via a specialist antiviral testing laboratory in Melbourne," said chief executive Jackie Fairley.

"We are very pleased to find that the compound is highly active against the coronavirus that causes COVID-19 and we are now exploring a number of product opportunities, including a potential preventative application to reduce the risk of infection."
 
I'm dendriming of a wiped carn'ovirus
just as it was before it showed...

Sorry Bing (and ASF) haven't taken my medications yet
 
Well that burst didn't last.
If there is anything in it, it might bounce back.
 
Knobby22 said:
Well that burst didn't last.
If there is anything in it, it might bounce back.
Click to expand...
Well if they come back with another round of good results then that bounce will probably be much more impressive. There are so many 'promising' cures out there who knows what is going to be that magic elixir. Some of it very dubious and hard to believe!!
Anyway Gotta go! I have to have my 3 turpentine soaked frog eyes for me sore back, and a garlic and pickled onion poultice to fix me dodgy knee.
 
I am picking SPL for this months Tipping Comp. IF they get a decent coronavirus follow up test results out (in May) that furthers their results then the price might climb dramatically (and hopefully stay up).
But they better not dilly about or antiseptic injections may pip their market. :smuggrin:
 
StarPharma slowly kicking goals, announcement by announcement and some bigger investors getting on board. Latest announcement is the launch of the product in more European countries. I think the USA will start getting a black market supply if the don't get round to approving it soon. Increasingly confident. I just need the price to take off before the end of the year. Wondering if I should buy more.
 
Yes, definite accumulation taking place.
Maybe the possibility of more contracts with the dendrimer tech.

My pick for the month. Though I am only hoping for a modest rise I am expecting a fall for the overall market.
 
Knobby22 said:
Yes, definite accumulation taking place.
Click to expand...
Is this you buying more Knobby?
:) good luck for second spot in the comp too.
I hope this innovative dendrimer development further proves to be a very effective and very successful in cancer treatment. Aussie Innovation from the ground up.
Haven't heard anymore about the dendrimer SPL7013 being further developed for covid19. This will put a rocket on prices if more encouraging findings are released.
 
No, I have enough jb.
But if you look at the way the shares are being bought it looks to me like someone wants a lot of them. Slowly forcing the price up while selling at the end of the day to try to keep it down.
 

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