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SLA - Solagran Limited

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"I've used the sauna treatment and it is damn good....."

Anecdotal evidence is wonderful, but it doesn't hold for a medical/health product.

q: Does Professor Con Stough have a commercial holding in this stock?

I admit, that from this extremely limited trial (25 patients were treated with Ropren - a study like this has virtually no statistically significant power whatsoever), initial results are bound to look good.

For example , what I mean is that if you test Ropren on 3 people, and 2 have a benefit, you can easily say 70% of participants showed marked cognitive increases!!! However, you and I know this number has no statistical significance.

Realistically, this study needs to be carried out on thousands of volunteers.

I am actually SURPRISED that the sample was so small, given the huge number (increasing all the time) of patients with Alzheimers disease, the trial could and should have been much larger.

As a natural therapy, this shows early promise, but there are many unanswered questions, so my opinion remains unchanged, and I still don't believe the hype yet.

edit - tell you what, it doesn't really matter what I say, there seems to be more people on your side anyway, as the stock price is rising.

Best of luck with your trading!
-Caliente///.
 
did this forum just push the price up today by 7cents because it looks like their a long long way from making these products commercially.
correct me if im wrong but these are all preliminary trials..... clinical trials can take up to 6 years to confirm dosage, efficacy or tolerability. to be marketed do they need to complete these clinical trials????
 
killer said:
did this forum just push the price up today by 7cents because it looks like their a long long way from making these products commercially.
correct me if im wrong but these are all preliminary trials..... clinical trials can take up to 6 years to confirm dosage, efficacy or tolerability. to be marketed do they need to complete these clinical trials????
Click to expand...

NO I DIDDNT DO A GODDAMN THING....EXCEPT BUY 2500 ON THE BELL SAW IT COME UP ON THE NEWS TICKER IN ETRADE...(LOVE THE TICKER)...NOW I HAVE 6,500 SHARES...JUST LIKED IT!...NOT TRYING TO WIN THE NOVEMBER COMP.....DYOR...IT'S AS GOOD AS IT GET'S.....I ONLYHAVE SMALL PARCELS OF SHARES i LIKE....EXCEPT FOR NEO......HEHE!
 
Thanks for the information Caliente, its good to see a less positive view on SLA. Some posters on other forum sites are really getting carried away with this release and predicting all sorts of things.

What's your view on SLA making Ropren a commercial success?
 
Drunk on my own sucess....yup!....research their ASX announcements...and see you in 2-3 years begging your doctor to prescribe it...and in 5-10 using it on a daily basis to brush your teeth with it!...lol all the way to the bank!

Oh...see who wins the monthly comp...maybe me!......:)....maybe not....I don't care...it's a good thing for my mates here who want in on it!!!!....I'm no show pony mate!!!!!!
 
36% on news for a small priced stock.....there is a lot more to this than just my ramping.....see you in the millionares club!....lol...I seriously only have 6500 shares!...want it confirmed?....I can show anyone you like in Perth right now!
 
pacer said:
Wouldn't it be nice to find out it CURES a few common bad diseases and got some big TV exposure......then we could see the 10 year graph looking like a big bowl...................so we have something to put all those profits into, lol.

Anyway here's the story I heard about how they got started.

When they just started, and were called Travelshop, one of the directrors was over in Russia sorting out the new booming USSR side of the travel business, just after 9/11 happened and the s/p was skydiving because no-one wanted to travel.
Lamenting the company's severe troubles and sitting in a bar getting sloshed on vodka, he struck up a conversation with an equaly sloshed Russian scientist, who was lamenting the countries troubles and the useless government, and also the fate of the research he was working on, due to the fact the govt. was more interested in other things at the time.
Anyway after a great night out with more booze and a couple of Russian spunks, they swapped numbers and kept in touch.
A few months later the directors were in a pub getting sloshed and lamenting the rapidly dying Travelshop, when he started talking about the Russian trip and his mate over there, and his research, when in a haze of booze fueled discussion they had commited themselves to sell Travelshop, go to Russia, drink lots of vodka, meet lots of Russian babes and catch up with this Russian scientist to see what coud be done about his predicament.
After a few weeks there they had managed to convince Russian officials, with bottles of vodka and Russian babes, that the only way to make any use of this research was to let a private company in on the act, papers were signed, patents applied for and here we are today, sitting on what is potentialy a huge company.

I think I was drunk on vodka when I heard this story but I think I got it right...............:cautious:
Click to expand...


This was me having a laugh.....now I'm serious! :eek:
 
Ok, I've found ONE article on ropren in the entire Medline archive in a journal called "Doklady Biochemistry & Biophysics", a russian health/medical journal.

The article is called

A comparative study of the effect of the polyprenol preparation ropren from coniferous plants on the key enzymes of the cholinergic and monoaminergic types of nervous transmission

published in December 28, 2005.

I have added it in for perusal.

Briefly browsing this article, it appears that animals were given ropren in doses between 40mg to 2000 mg, for variable period of time. After this, their body parts; brain, liver etc. were frozen centrifuged, and then levels of CE (cholinesterase) and MAO (monoamine oxidase) analysed.

The anticholinesterase activity looks promising, but monoamine oxidase was ineffective at the liver except at high doses (2000 mg > 50 times the lowest dose).

Once a baseline is established, its cost will be essentially proportional to the dose, double dose is close to double the price, so the liver therapy may be quite expensive. Given that liver transplants cost hundreds of thousands of dollars each, there may be a market here too, however I have yet to see ANY journal article on the effectiveness of ropren in liver disease.

Off topic, I read somewhere, there is total annual production of 24kg atm, which will be ramped up to several hundred kilos. The small quantity alone should be encouraging for investors from a supply/demand perspective.

imo, this drug/herbal supplement does appear to have tangible pharmacological benefits and will appeal to a different corner (alternative medicine end) of the market.

Thus if it breaks into western markets, particularly the US yes, the potential is significant.
 

Attachments

  • Ropren article.pdf
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hi Caliente, theres a heap more info on ropren (or bioeffective R) in past asx announcements by solagran, including how the potential sales in russia for liver treatment alone could be absolutely massive, and how it out performed essentiale forte, one of the most commonly used drugs in the word to treat liver cirrhosis, in russian trials. not to mention its a non toxic drug with no found side effects and russian hospitals want it. anyway dont take my word for it cause im a holder, but in my view its definately worth reading up on this drug.
cheers
 
Russia just got out of the cold war.....the best things about Russia are only just starting to come to light...and I don't mean Kostya Tsu or mail order brides...lol

You would still have a hard time finding certain things from the USSR on the net, as it has been such a controlled society for so long...and isn't exactly fully open yet.

It will take many years to come before even a small percentage of Russian archives are open and available on the WWW.

Read all the ASX announcements over the last 6 months on this, and you can see this going places big time!.....It has even just convinced an Aussie skeptic professor(see the latest ASX announcement)...down ramp all you like but the SP rise today just confirmed my faith here....not as a miracle cure for every disease on the planet, but as a genuine way to inhibit and control degenerative conditions, and even reverse the condition (but not eliminate it) somewhat.....

Faith, in the abilities of this new (well not so new...Russians have been using it for over 50 years) and facinating natural substance, will have health implications in itself....I only hope BEROCCA catch on to this...my favorite drug of choice next to the odd Bourbon....lol

I realy only bought these shares for a laugh.....cure cirrhosis of the liver...yeah right....but I may need it soon...Burp!...hehe...:eek:
 
Caliente said:
Ok, I've found ONE article on ropren in the entire Medline archive in a journal called

Ummmm one more thing Caliente....you said 24 kg/year is currently being produced......was independantly valued at $1,000,000 per kilo....24x$1mill....that's equal to the current market cap after today(possibly), and they have just done a deal with a manufacturer to "produce hundreds of kilos of the stuff", you said....

Well do the math my friend....:).....let's see where it takes us.
Click to expand...
 
Ropren is a relatively new name, its solagrans finished form of bioeffectve R. if people read SLAs past announcements they will find a heap of info on bioeffective R, all good.

cheers
 
There goes my prize for the stock picking comp....had a feeling it'd drop......may be the next ann will be better.
 
TRADING HALT!

Take over offer, partneship, capital raising, major medical result (Good/bad), .....What could it be I wonder, any other ideas?
 
Gotta be good news Pacer, I've been watching but haven't got on board so no jinx from me mate. The sp will double now just to p**s me off. :p:
Good Luck! :D
 
OTS......I think it may be that they have snaffled a mojor supply contract to a major health supplies company.....they have been in talks for a while now I think.......agreed.....it is has to be good news......:)......we haven't had anything but good news for the last 4 months and has realy been quite amazing....surprised it's not sitting above 50c already.......ramp ramp...:p:
 
Well, Pacer, I haven't researched this one, but I did notice that many microcap Biotech companies have a habit of cranking out announcements very regularly. They tend to describe future market potential in the billions of dollars, etc. etc. They conveniently neglect to mention that they are not likely to get more than 0.01 % of that future market within the next 5 years. Only a few of them manage to stay afloat long enough to see their product(s) to market. But your comments are definitely good for a chuckle and a punt is a punt .. :p:
 

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