Australian (ASX) Stock Market Forum

MSB - Mesoblast Limited

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Got out a couple of days ago.

Looking forward to getting back in.
Down 10%. Gambling really isn't it.
 
there was a big "but on the other hand" write-up in the AFR over the weekend. Flattering to get the attention, but the pitfalls and challenges of serial cash calls, and failure to convert with big pharma, came across loud and strong:
Entering the ASX/200 should be a moment of celebration for any biotech start-up. For Silvio Itescu, the multimillionaire founder and chief executive of stem cell group Mesoblast, it should be an even-greater triumph after a fourfold surge in the stock price spurred by an announcement that the company was assessing one of its drug candidates as a treatment for COVID-19 patients. On June 12, Mesoblast re-entered the ASX/200 as other healthcare companies Estia Health and Mayne Pharma dropped out.
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But it's been a roller-coaster ride and Itescu is still fending off critics. They say he is yet to prove the company's worth at over $2.3 billion, and note the regenerative medicine group is yet to produce a major commercial product despite raising over $1 billion in fresh equity since listing on the ASX in 2004 at just 50¢ per share. Long-time backers .... say Mesoblast is on the cusp of the next frontier in medicine. .....But critics ask why, if its prospects really are so good, some voracious pharma giant hasn't bought Mesoblast out or partnered with it after the better part of two decades plying its trade?....
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https://www.afr.com/companies/healthcare-an...20200611-p551m3

Despite the big name support, the market is still split. Several analysts and fund managers say they lost interest after it failed to deliver on its "big promises" for many years.

"They have been just around the corner (from the next big breakthrough) for some time," says a portfolio manager. "Investors in this space do need to be patient. But good drugs don't tend to jump from indication to indication. I think Mesoblast started off in arthritis and now they're looking at COVID-19. They must've have tried at least ten indications.".....
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Last edited:
UMike said:
Got out a couple of days ago.

Looking forward to getting back in.
Down 10%. Gambling really isn't it.
Click to expand...
Was kicking myself a week or so ago for not getting back in at the low $4s as it got close to the high $5s

Down over 25% today. A top 200 Company. Strange times.
 
UMike said:
Was kicking myself a week or so ago for not getting back in at the low $4s as it got close to the high $5s

Down over 25% today. A top 200 Company. Strange times.
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Yes I was congratulating myself, up heaps then right back down to where it was in one day. Too many jumpy traders. I am trying to ignore the gyrations.
 
Big drop today: closed at $3.36 (yesterday's close $4.87)

There seems to be much divided opinion about what the US regulators are actually going to grill Mesoblast about.
https://www.businessnewsaus.com.au/...ent-for-bone-marrow-transplant-condition.html

At best it's a show - us - what - you - got, so - we - can - tick - it - off
at worst it's a not - good - enough, - go - back - and - do - it - again.

Market dump on open, before today's clarification announcement from MSB:

https://www.asx.com.au/asxpdf/20200811/pdf/44ldcp6hdr4tt4.pdf

Hmm, big dump before ann? Still a couple days ahead of next regulators meeting?
Now isn't that interesting?
Could it be insiders know the grilling will be hot?
Or just scaredy-cats spooked by each other?

Discl: Don't hold at present.
Discl: and that's only because Monday's price hit my happy-point, and I sold ($4.66)
Whew!
 
Purple XS2 said:
Big drop today: closed at $3.36 (yesterday's close $4.87)

There seems to be much divided opinion about what the US regulators are actually going to grill Mesoblast about.
https://www.businessnewsaus.com.au/...ent-for-bone-marrow-transplant-condition.html

At best it's a show - us - what - you - got, so - we - can - tick - it - off
at worst it's a not - good - enough, - go - back - and - do - it - again.

Market dump on open, before today's clarification announcement from MSB:

https://www.asx.com.au/asxpdf/20200811/pdf/44ldcp6hdr4tt4.pdf

Hmm, big dump before ann? Still a couple days ahead of next regulators meeting?
Now isn't that interesting?
Could it be insiders know the grilling will be hot?
Or just scaredy-cats spooked by each other?

Discl: Don't hold at present.
Discl: and that's only because Monday's price hit my happy-point, and I sold ($4.66)
Whew!
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Its always going to be a long haul when dealing with the FDA.

gg
 
In with system on monday out yesterday, loss of $700 or 16%
And this was selling on manual sl at 3.8
Outch
 
MSB is under trading halt
https://www.asx.com.au/asxpdf/20200813/pdf/44lgy1xr5k6sv4.pdf
Meeting with Oncology Drug - after FDA's not very encouraging advise.
Could the cat is coming out of bag tomorrow after market gone up by 10% today ?
Unloading not by a big amount if you see 1% , but read the volume - massive
- https://www.asx.com.au/asxpdf/20200812/pdf/44lf016py149pw.pdf
Fool presented this double edged story - head I win, tail you loose.
https://www.fool.com.au/2020/08/13/down-37-in-2-days-is-the-mesoblast-share-price-a-buy/
 
I don't get it.
The results are good. It is being used in Japan.
CSL and others are developing similar drugs based on similar technology.
It saves little kids.

If it's about delaying it so competors can catch up then it's disappointing.Will be very interested in this announcement.
 
qldfrog said:
So expect up the roof today?
And what is up the roof after this week fall?
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I guess so, maybe on the chimney even, straight to $5 on open.

Still has to get final FDA approval but from what I gather the FDA has never knocked back anything voted for by ODAC. Not many Stem Cell therapies seem to have been approved by the FDA so if it passes could be good news for other MSB Phase 3 Trials.
 
wabullfrog said:
I guess so, maybe on the chimney even, straight to $5 on open.

Still has to get final FDA approval but from what I gather the FDA has never knocked back anything voted for by ODAC. Not many Stem Cell therapies seem to have been approved by the FDA so if it passes could be good news for other MSB Phase 3 Trials.
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Yes i put a buy on open but did not want to go silly.this is not tesla yet:)
Order deleted
 
wabullfrog said:
I guess so, maybe on the chimney even, straight to $5 on open.

Still has to get final FDA approval but from what I gather the FDA has never knocked back anything voted for by ODAC. Not many Stem Cell therapies seem to have been approved by the FDA so if it passes could be good news for other MSB Phase 3 Trials.
Click to expand...
https://www.asx.com.au/asxpdf/20200814/pdf/44lhlqglc3y569.pdf
@wabullfrog You were very close to expectation on going through roof :). It went up by 40%. More analysis and buying would consolidated the price I believe. Just bought couple of days back and not complaining some astute gamble :) :).
No BS, it was a gamble and did not put money excessively either thinking the result could have gone south.
upload_2020-8-14_9-25-20.png
 
Miner said:
https://www.asx.com.au/asxpdf/20200814/pdf/44lhlqglc3y569.pdf
@wabullfrog You were very close to expectation on going through roof :). It went up by 40%. More analysis and buying would consolidated the price I believe. Just bought couple of days back and not complaining some astute gamble :) :).
No BS, it was a gamble and did not put money excessively either thinking the result could have gone south.
View attachment 107554
Click to expand...

@Miner I did similar. Wednesday buy, small parcel, near the bottom.
 
My tip for the month.
I know it has risen to $5.28 and we still have a month to go to get the results from the various trials but it has formed a base and is ready for the next leap forward, hopefully to $8. We know the price can often rise in anticipation.
 
I've been holding MSB for 10 years or more, and have seen rises to $9 mark, then big falls as they listed on US market. I did what Knobby22 says:
Knobby22 said:
I am trying to ignore the gyrations.
Click to expand...

I was lucky enough to double up holdings when Covid crash reduced them to mid $1 range.
I truly hope that youre correct Knobby22:
Knobby22 said:
and is ready for the next leap forward, hopefully to $8.
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To me it would be reward for a long held hope! :)
(Next the Dockers would win the Premiership too!!) ROFL.
 
Some good news. Interim results for Covid 19 phase 3 trials were such that the regulator recommend they continue.
We will get final results 4th quarter.
 

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