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Ok, I'll qualify my comments on anti-depressants, my Father nearly killed himself on the Zoloft ****, so I'm coming from somewhat of a qualified position.As a sufferer of Depression I think comments like this shouldn't be thrown around willy nilly.
Depression is a complicated/complex issue that needs to be discussed with the appropriate people. Find a doctor that you like and trust and discuss the pros and cons of anti-depressants with him/her. In my opininion they have their place in treatment but can also sometimes make things worse.
I know what you mean, Pager. I have a daughter who has battled on and off with depression for years. She now has two children, the youngest just over a year old and postnatal depression has bitten hard... And we are pretty much the only real support she has - not an easy road by any means.Its not only the person suffering from depression that’s affected often it has an impact on their whole family....
Thanks for sharing, MRC. Yes, pretty much what I have been doing and is what her doctor recommends as well, but it is quite exhausting at times. And I want to be able to look back later without regrets and know I gave her the best chance of recovery that I possibly could.Some advice I can give you Sails, is give her as much support as you POSSIBLY can.
I supported my father a lot, but I feel sometimes I sort of hid from it to safeguard my own health. However, I realise now I could have done a lot more than I did (ultimately, it might not have made a big difference), but I still could have tried. Also, I think its important to try and compliment your daughter as much as possible and just hang out with her and listen a LOT without offering too much advice.
Just what I learnt from my scenario. If it means anything at all.
Good luck!
Yes, I suffer from numerous afflictions.
Depression, Generalized anxiety, Bi-polar, OCD, & to top it off a hint of a personality disorder.
But, it seems to be all intertwined ; as when I feel happy, I'm no longer anxious, obsessive, or malicious.
I have been out of the rough patch for a while now; not as a result of medication (I found it absolutely awful; the side-effects ...), but just eating healthy, not fretting over the future, vitamins & fish oil seems to help (placebo, anyone?
I tried psychotherapy for a while ... didn't find it beneficial, it actually made things worse for me, triggered anger I guess. All of my problems stem from hurt / anger ... awful childhood, I actually envy those who actually feel love for their family, love was an emotion up until recently I had never felt!
For well over 6 years I wanted to die, I guess you could say I tried a couple of times as well; yeah, life hasn't been all that swell!
For those who have seen my usual posts, you'll be shocked to see me talking seriously!: Humour has always been a mask to hide the sad feelings, even though I'm no longer really sad ... I guess the humour stuck around!
I'm sure that this is the case 75% of the time. Not accepting this leads to "real" depression in lots of cases. In my case accepting this was a way out that antidepressents did not fix. Just pointing this out plus showing that others are much worse off can help in lots of cases.Sometimes I feel our expectations of life are too high. It's just not realistic to be happy all the time. Bad stuff happens and it's reasonable to feel distressed about that. And sadness and grief are normal parts of an ordinary life.
I didn't find any of the professionals particularly useful. A volunteer counselling service where they simply listened and not much more was the most helpful, as well as a few very good friends who also simply listened and offered encouragement and support as I worked my own way out of the situation.
Hi,
I found the same thing. I've been diagnosed with agoraphobia/depression, and I found the way the medical profession concentrated on what was "wrong" with me was really defeating and made me worse. The same with well meaning friends who want to help. They get so caught up with "helping" me that they start seeing me as an illness and not as a person. I remember sitting in a room once with a doctor and my family, they were all discussing what I should do ... and they left me completely out of the conversation.
The people who have helped most are the ones who just accept me, with all my quirks, and let me get on with the job of getting better.
The hardest part of dealing with the illness has been dealing with other peoples perceptions of it.
cheers
Mouse
From The Times
February 26, 2008
Depression drugs don’t work, finds data review
Prozac
David Rose
Millions of people taking commonly prescribed antidepressants such as Prozac and Seroxat might as well be taking a placebo, according to the first study to include unpublished evidence.
The new generation of antidepressant drugs work no better than a placebo for the majority of patients with mild or even severe depression, comprehensive research of clinical trials has found.
The researchers said that the drug was more effective than a placebo in severely depressed patients but that this was because of a decreased placebo effect.
The study, described as “fantastically important” by British experts, comes as the Government publishes plans to help people to manage depression without popping pills.
* Depression: your questions answered
* Dr Thomas Stuttaford answers your questions on antidepressants and Prozac
* Dr Thomas Stuttaford answers your questions on depression and therapy
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More than £291 million was spent on antidepressants in 2006, including nearly £120 million on SSRIs. As many as one in five people suffers depression at some point. With that in mind, ministers will today publish plans to train 3,600 therapists to treat depression. Spending on counselling and other psychological therapies will rise to at least £30 million a year.
The study, by Irving Kirsch, from the Department of Psychology at the University of Hull, is the first to examine both published and unpublished evidence of the effectiveness of selective serotonin reuptake inhibitors (SSRIs), which account for 16 million NHS prescriptions a year. It suggests that the effectiveness of the drugs may have been exaggerated in the past by drugs companies cherry-picking the best results for publication.
The National Institute for Health and Clinical Excellence (NICE), which is due to review its guidance on treating depression, said that it would consider the study.
Mental health charities say that most GPs admit that they are still overprescribing SSRIs, which are considered as effective as older drugs but with fewer side-effects. SSRIs account for more than half of all antidrepressant prescriptions, despite guidelines from NICE in 2004 that they should not be used as a first-stop remedy.
American and British experts led by Professor Kirsch examined the clinical trials submitted to gain licences for four commonly used SSRIs, including fluoxetine (better known as Prozac), venlafaxine (Efexor) and paroxetine (Seroxat).
The study is published today in the journal PLoS (Public Library of Science) Medicine. Analysing both the unpublished and published data from the trials, the team found little evidence that the drugs were much better than a placebo.
“Given these results there seems little reason to prescribe antide-pressant medication to any but the most severely depressed patients, unless alternative treatments have failed,” Professor Kirsch said. “The difference in improvement between patients taking placebos and patients taking antidepressants is not very great. This means that depressed people can improve without chemical treatments.” He added that the study “raises serious issues that need to be addressed surrounding drug licensing and how drug trial data is reported”.
The data for all 47 clinical trials for the drugs were released by the US Food and Drug Administration under freedom of information rules. They included unpublished trials that were not made available to NICE when it recommended the drugs for use on the NHS. “Had NICE seen all the relevant unpublished studies, it might have come to a different conclusion,” Professor Kirsch said.
Tim Kendall, a deputy director of the Royal College of Psychiatrists Research Unit, who helped to formulate the NICE guidance, said that the findings were “fantastically important” and that it was “dangerous” for drug companies not to have to publish their full data. He added: “Three of these drugs are some of the most commonly used antidepressants in this country. It’s not mandatory for drug companies to publish all this research. I think it should be.”
SSRIs are not prescribed to patients under 18 because of the risk of suicide.Drugs watchdogs in Europe are considering tighter controls on the development of new medicines, The Times reported this month, and may soon require regulators to monitor psychiatric effects and the risk of suicide more closely during clinical trials.
A spokesman for GlaxoSmithKline, which makes Seroxat, said: “The authors have failed to acknowledge the very positive benefits these treatments have provided to patients and their families dealing with depression and their conclusions are at odds with what has been seen in actual clinical practice. This one study should not be used to cause unnecessary alarm and concern for patients.”
A spokesman for Eli Lilly, which makes Prozac, said: “Extensive scientific and medical experience has demonstrated that fluoxetine i an effective antidepressant.”
FYI, I spotted this article in todays paper. Could this be true?
http://www.timesonline.co.uk/tol/life_and_style/health/article3434486.ece
Chops, Prozac is included in the 'ineffective' group.The new generation Anti-deps are largely ineffective. There is only 4 or 5 (aside from tricyclics, prozac being one of 5) that I know of that actually work at a statistically significant level above the placebo rate. Tricyclics are actually very effective, but very old, so they are all generic, hence, no money. Same with prozac... more effective than just about any new anti-dep.
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