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Vitamin D changes everything

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Vitamin D changes everything
What we think is normal is instead really just broken



We just don't know !..
We only know what happens
In Vitamin D deficient Populations


Motorway
 
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FACT VERSUS THEORY

Who thinks wheat bran is good for them ?


In the early 1970s two young Americans, Frank and Cedric Garland, who
were studying science and medicine, made an epic journey across America
from San Diego, California, to John Hopkins Medical School on the east coast.
The brothers rode proudly in a 1972 Mustang Sprint Fastback with blue trim.
As they crossed the country from west to east, returning from their Christmas
vacation, they could not help noticing the dramatic change in weather from
sunshine to snow. It was this journey that gave the Garland brothers the first
clue about the cause of bowel cancer.

At that time the most popular scientific theory was that insufficient dietary fibre
was the cause of bowel cancer.
The English surgeon, Dennis Burkitt, gained fame
from his animated lectures illustrated with snapshots of African faeces. He
pointed out that colorectal cancer is rare in Africa and was relatively rare in
modern industrial countries before the 19th century.

Burkitt argued that
colorectal cancer is a disease of civilisation caused by refined diets. His message
was widely accepted and many people started to eat more fibre, especially in the
form of bran. The food industry showed what they can do when given a clear lead
– many foods began to appear on supermarket shelves with added fibre,
especially bran.

In an important article on diseases of civilisation in the British Medical Journal47a
in 1973 Burkitt said that a carcass in the African bush is most easily discovered by
locating telltale vultures and the same approach is needed in medical research. In
fact Burkitt was misled by his vultures, at least so far as bowel cancer is
concerned.

The hard stools passed by civilised Britons do not seem to be the
primary cause of colon cancer. It was the Garland brothers who, following their
epic journey in the Ford Mustang, obtained the first evidence showing that it is
lack of sunshine and vitamin D that are a more significant cause of bowel cancer.



When the famous Dr. Denis Burkitt noted that "diseases of civilization" were rare in Africa””although many patients died of malaria or gastrointestinal diseases””he was working in Uganda, right on the equator.

What Dr. Burkitt failed to notice, when he hypothesized it was fiber in the diet that prevented the diseases of civilization, was his patients frequently wore little clothing and were under an equatorial sun 365 days a year. Dr. Burkitt thought it was fiber, but it was the vitamin D.


As far as dying, remember, everyone who takes Vitamin D will die. It's simply a question of when. What we hope, even expect, is vitamin D will square off the mortality curve. Now, people start dying from the diseases of civilization in their forties, struck down by heart disease, cancer, etc. Premature deaths accelerates in the 50s and are in full swing by the 60s.

That is, the mortality curve slops downward, beginning in the late 40s, people succumbing to the diseases of civilization. Perhaps vitamin D will allow people to live normal lives until they reach their 90s–100s, when we will all suddenly drop dead of old age!

Quotes from http://www.vitamindcouncil.org/
may be reproduced as long as you properly and prominently attribute it's source. Please reproduce it, post it on Internet sites, and forward it to your friends.



Pic is Truganini and last 4 Tasmanian Aborigines

See the clothes ? Dark Skin in Tassie ?
And diet they were given at this stage ?

How many native peoples
Did Vitamin D deficiency finally Kill off
after everything else did it's work.

Motorway
 

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I was a little worried that my D levels may not be up to spec, but some research seems to suggest that getting enough from the sun shouldn't be that hard:

from: http://www.sunshinevitamin.org/

Sunlight Exposure (full body exposure)* 3,000 – 20,000 IU

* Sun exposure to the arms and legs for 10-15 minutes. The amount of vitamin D produced depends on the intensity of the UVB in the sun and many other factors. Darker-skinned individuals may need 5-10 times more exposure than a fair-skinned person to make the same amount of vitamin D.

from: http://www.darksideoftanning.com.au/get_facts/download.aspx#vitamin_d

The Australian climate, with hot summers and clear skies has plenty of UV radiation, so most Australians make enough vitamin D through sun exposure by following their regular day to day routines, even when protecting themselves from the sun. Keep in mind the following tips:

* Always protect yourself from the sun during peak UV periods (when the UV Index in above 3).
* In NSW from August to May, six to eight minutes of sun exposure to the face, hands and arms (15% of the body) on most days of the week at times when the UV index is below 3 (before 10am and after 3pm daylight savings time) is all the sun exposure a fair skinned person requires for vitamin D production.
* In June and July this may increase to 40 to 50 minutes.
* Short bursts of sun (outside peak UV periods) are better for making vitamin D than long periods, as the body can only absorb a set amount at a time.
* Your body can rely on its stores of Vitamin D for 30 to 60 days.
* Exposing your skin to the sun when the UV Index is above 3 increases your risk of developing skin cancer.
* Exposing yourself to UV radiation in a solarium is a not an effective way to obtain vitamin D and will damage your skin and increase your risk of developing skin cancer.
* Look after your bones by maintaining a healthy diet, exercising regularly and knowing when to protect your skin.
 
Do people who worry about Vitamins suffer more constipation than the average poster on ASF.

I believe they do, as a non sufferer.

How can we as a community of investors help them?

gg
 
Thanks for the info, Motorway...:)

I think some over zealous Mums don't give their kids even a few minutes in the sun. I know of one such mother who is a school teacher. She rushes around with hats and sunscreen and has spares for other kids. She was horrified when I politely rejected her offer of a hat for my granddaughter - it was late in the afternoon! I said something about getting enough Vit D and she looked at me as if I was being negligent!

Her two children are unusually pale and I wonder if she will one day regret protecting so tightly. Sure they won't get skin cancer, but with the lack of natural Vit D, I wonder if she is inadvertantly opening them up to other problems with this almost fanatical approach.

I have also done a lot of research on osteoporosis and soon learned the value of Vit D. As it is inadvisable for me to take the pharmaceutical medications, my GP allowed me to try Strontium (not the radioactive kind) together with calcium, Vit D, Vit K and a few other trace minerals. I did extensive research on it and was only able to find very positive feed back.

I had been losing bone density on every dexa scan for the last few years so something had to be done. After 18 months on Strontium, the dexa scan showed an average of 5% increase. My GPs jaw litterally dropped at the result of not only stopping the decrease but such a significant increase in that time...:) I do know that strontium can be heavier than calcium, but read somewhere that they are no longer adjusting the scores. I told the radiologist that I was on it so they were fully aware.

A few months before the scan, I fell down about a half flight of stairs. Fell sideways and crashed down on to a tiled floor. Amazingly, nothing was broken! So I felt that the strontium must have been somehow strengthing the bones and possibly making them a bit less brittle.

You seem quite knowledgeable on these sorts of things, Motorway. Do you know anything about strontium for osteoporisis in addition to Vit D?

I thought it worth mentioning here in case it should help anyone else who can't take the pharmaceutical alternatives.
 
* Always protect yourself from the sun during peak UV periods (when the UV Index in above 3).

You need the UVB
UVB only makes up a small % of solar radiation

It only reaches the ground when the sun is Above 45 degrees
IE your shadow is shorter than you are...

More as been learnt about vitamin D in the last year than the last ten
and In the last Ten than ever

So there is much ignorance ( I have seen this with Doctors )

To make Vitamin D from the SUN you need to expose a significant amount of skin probably over 70%.... This is because UVA destroys Vitamin D after a time

So more skin exposed for a shorter time in the middle of the day
rather than less skin for a longer time..Or exposures at morning or late afternoon..

If the UV index is only 3 I would doubt you will make any Vitamin D..

OK what about Melanoma and Skin cancer ?

Remember most people who go out in the SUN are Vitamin D deficient
They get Sunburned and it takes a couple of months to build up levels in the body

This is not what many do.. But get intermittent Burning

Sunburn is a sign of low vitamin D levels..

This is incredibly interesting and slightly counter intuitive
And HEALTH and WELLBEING start here..

I supplement with Vitamin D and enjoy the SUN
I find I do not even go PINK in SUN anymore ( I used to burn very easily and avoided the SUN )

YOU DO NOT WANT TO GET SUNBURNED

But the same vitamin D that protects against major cancers
Also protects against Melanoma..

But for reasons I will post
Vitamin D levels need to be both adequate and stable throughout the year
Fluctuating levels are not healthy


Increased UVA exposures and decreased cutaneous Vitamin D3 levels may be responsible for the increasing incidence of melanoma☆

Dianne E. Godara, Robert J. Landrya, Anne D. Lucasa
Received 6 June 2008; accepted 12 September 2008. published online 20 January 2009.

Summary
Cutaneous malignant melanoma (CMM) has been increasing at a steady exponential rate in fair-skinned, indoor workers since before 1940. A paradox exists between indoor and outdoor workers because indoor workers get three to nine times less solar UV (290–400nm) exposure than outdoor workers get, yet only indoor workers have an increasing incidence of CMM. Thus, another “factor(s)” is/are involved that increases the CMM risk for indoor workers.

We hypothesize that one factor involves indoor exposures to UVA (321–400nm) passing through windows, which can cause mutations and can break down vitamin D3 formed after outdoor UVB (290–320nm) exposure, and the other factor involves low levels of cutaneous vitamin D3.

After vitamin D3 forms, melanoma cells can convert it to the hormone, 1,25-dihydroxyvitamin D3, or calcitriol, which causes growth inhibition and apoptotic cell death in vitro and in vivo. We measured the outdoor and indoor solar irradiances and found indoor solar UVA irradiances represent about 25% (or 5–10W/m2) of the outdoor irradiances and are about 60 times greater than fluorescent light irradiances.

We calculated the outdoor and indoor UV contributions toward different biological endpoints by weighting the emission spectra by the action spectra: erythema, squamous cell carcinoma, melanoma (fish), and previtamin D3. Furthermore, we found production of previtamin D3 only occurs outside where there is enough UVB. We agree that intense, intermittent outdoor UV overexposures and sunburns initiate CMM; we now propose that increased UVA exposures and inadequately maintained cutaneous levels of vitamin D3 promotes CMM.



Some interesting facts cited in support of their hypothesis:


"Although outdoor workers get much higher outdoor solar UV doses than indoor workers get, only the indoor workers’ incidence of cutaneous malignant melanoma (CMM) has been increasing at a steady exponential rate since before 1940."
"Outdoor workers have a lower incidence of CMM compared to indoor workers."
People who use UVB-absorbing sunscreens have a significantly increased risk of melanoma and these sunscreens promote the growth of melanoma in mice.
People who maintain an all-year-tan have a reduced risk of melanoma, and outdoor workers, who receive three to nine times the erythemally effective UV dose of indoor workers have a significantly lower incidence of melanoma.

Excluding sunburns, outdoor activities in childhood decrease the incidence of melanoma and research has failed to find a ‘‘critical period,” such as childhood, where intense exposures contribute more towards the induction of melanoma.
Sunburns throughout life increase the risk of melanoma, while low level solar UV exposures reduce the risk.


Melanoma patients who receive regular sun exposures live longer than those who do not.

UVA not only promotes skin tumor growth in mice after initiation by artificial sunlight, but also causes twice as many tumors to form .
UVA increases melanomas in a mouse model after initiation by UVB.
People can get considerable UVA exposure from windows, but windows do not allow passage of adequate UVB to stimulate vitamin D production.
UVA exposure, absent UVB exposure, leads to degradation of vitamin D; and UVA also causes DNA damage.

"High-rise office buildings, needing many large windowpanes, became increasingly popular around the mid 1910s, about 20 years prior to the first observed increase in the incidence of CMM. The time-line for the industrial revolution fits the CMM observations, unlike the introduction of fluorescent lights in the mid-1940s [80] or any other events that occurred after the mid- 1930s. Thus, the industrial revolution caused many workers to stay indoors during the day reducing their cutaneous vitamin D3 levels and, the UVA entering their offices caused photodegradation of vitamin D3 and mutations to the DNA of their skin cells."
Finally:

"In the early 20th century, people went against evolution by going indoors during the day to work, which drastically decreased their daily amount of cutaneous vitamin D3 and, along with it, their blood levels. With the addition of larger buildings and sky scrappers, people created an unnatural UV barrier when windows were developed and used in abundance. The UV barrier created by window glass divided UVB from UVA, so that the vitamin D making UVB was excluded from our indoor working environment; only the vitamin D-breaking and DNA-mutating UVA was included. Because this unnatural UV environment existed for decades in buildings and cars, CMM began to steadily increase about 20–30 years later in the mid-1930s."


Fact is it is not just the incidence of Melanoma that is growing exponentially but all cancers

We hear of the breast cancer the prostate cancer the Bowel cancer epidemics
Asthma , Diabetes , Autism etc etc epidemics...

FACTS and THEORIES

I have seen dramatic health improvements in myself and loved ones..
So the desire to share some of my knowledge journey here

It is fascinating how one nutrient can do so much and the WHY

I will Say more on your important question Roland

But

If you are Vitamin D deficient anything will give you cancer ( In fact you can just get it without any outside cause . The communication between cells just breaks down )

Motorway
 
Motorway
Has your research sufficiently explained how people in extreme latitudes get sufficient Vitamin D? Wouldnt it be assumed that where the sun was not available or the weather so cold for long periods that cancer rates and other health issues would then be measurably higher than otherwise?
 
Thanks for the info, Motorway...:)

I think some over zealous Mums don't give their kids even a few minutes in the sun. I know of one such mother who is a school teacher. She rushes around with hats and sunscreen and has spares for other kids. She was horrified when I politely rejected her offer of a hat for my granddaughter - it was late in the afternoon! I said something about getting enough Vit D and she looked at me as if I was being negligent!

Her two children are unusually pale and I wonder if she will one day regret protecting so tightly. Sure they won't get skin cancer, but with the lack of natural Vit D, I wonder if she is inadvertantly opening them up to other problems with this almost fanatical approach.

I have also done a lot of research on osteoporosis and soon learned the value of Vit D. As it is inadvisable for me to take the pharmaceutical medications, my GP allowed me to try Strontium (not the radioactive kind) together with calcium, Vit D, Vit K and a few other trace minerals. I did extensive research on it and was only able to find very positive feed back.

I had been losing bone density on every dexa scan for the last few years so something had to be done. After 18 months on Strontium, the dexa scan showed an average of 5% increase. My GPs jaw litterally dropped at the result of not only stopping the decrease but such a significant increase in that time...:) I do know that strontium can be heavier than calcium, but read somewhere that they are no longer adjusting the scores. I told the radiologist that I was on it so they were fully aware.

A few months before the scan, I fell down about a half flight of stairs. Fell sideways and crashed down on to a tiled floor. Amazingly, nothing was broken! So I felt that the strontium must have been somehow strengthing the bones and possibly making them a bit less brittle.

You seem quite knowledgeable on these sorts of things, Motorway. Do you know anything about strontium for osteoporisis in addition to Vit D?

I thought it worth mentioning here in case it should help anyone else who can't take the pharmaceutical alternatives.

Hello Sails.. All life evolved under the SUN...( says it all... We are still here and life in its abundance on this planet ).. Our genes still think they are in Africa ...( We are a type of Ape All of which are only found in the tropic zones )

For strong bones you need Vitamin D , Magnesium , Vitamin K2-7 , Boron and I have seen Strontium mentioned...

The need for supplements of all kinds drastically falls when Vitamin D is right
EG Most people will get enough calcium in their diet ... But supplement a little if you need to.. Prehistoric man had incredible strong bones without any dairy !

Vitamin k2-7 ,Magnesium and Vitamin D, these are harder to get optimal amounts of in the modern diet
esp Vitamin D......

Weight bearing exercise is important for bones as well as muscle
Adequate protein ( Bones are living tissue ) ( long chain omega 3s fish oil are important )

But
Everything starts with Vitamin D
Evolution based it's most important control system on the one thing that could aways be countered on.. because it always shone anew everyday..
foods were seasonal and famines a reality...



Seen in the light of evolution, biology is, perhaps, intellectually
the most satisfying and inspiring science. Without that light it
becomes a pile of sundry facts some of them interesting or
curious but making no meaningful picture as a whole.

Motorway
 
Do people who worry about Vitamins suffer more constipation than the average poster on ASF.

I believe they do, as a non sufferer.

How can we as a community of investors help them?

gg

mmm, "worry" was a little exaggerated, I don't actually ever recall being constipated, all those spicy dishes and curries probably have me on the other side :)

GG, although I am aware that your comment was a light hearted one, but it does highlight the fact that there are many that have no desire to learn about nutrition and are quick to debunk or ridicule new findings.

Personally I find the subject fascinating, and if by chance, learning more about how our bodies work gives me an advantage, then that's a pretty good investment.
 
Motorway
Has your research sufficiently explained how people in extreme latitudes get sufficient Vitamin D? Wouldnt it be assumed that where the sun was not available or the weather so cold for long periods that cancer rates and other health issues would then be measurably higher than otherwise?

Yes the original peoples who moved north and south
where Hunters and esp Fisherman

eg Inuits eat nearly 100% such foods
The Original Tasmanians

Fish is one food that has very high levels of Vitamin D

When Caesar invaded Britain .. The Inhabits were dark skinned ...
They also were still hunting and living the old ways
As people gave up the old ways and became farmers of grains

( only from 10000 years ago less for many )

Much disease did eventuate

see the research on
Skeletons of paleolithic Peoples ( hunters gatherers Vs Neolithic farmers )

Major diseases of the 19th century were TB and Rickets...

Today there are many more diseases the further from the equator
IT IS A LONG LIST

Mutiple Scelrosis for example
various Cancers
Heart Disease
etc

Big Pharma would be all over the news if any drug would work 10% more than a placebo. Vitamin D => 80-96% ?

But It is NON PATENTABLE and is the cheapest nutrient supplement available to make.
There is no money for anyone to make here..
So you won't hear about it..

No conspiracy just the way things work !

Cenegenics ® Medical Institute, the global age management medicine leader, collaborated with Dr. Ernst R. von Schwarz””professor of medicine at UCLA’s David Geffen School of Medicine””to investigate current evidence linking vitamin D deficiency with heart failure. Their expert scientific review recently appeared in the Journal of Cardiovascular Pharmacology and Therapeutics.

The stats show why co-authors Cenegenics and von Schwarz zeroed in on vitamin D deficiency: An estimated 1 billion people worldwide have deficient or insufficient levels of vitamin D. Even more alarming is the association of vitamin D deficiency with many types of diseases, particularly heart failure.

In fact, epidemiologic studies show an 80% to 96% prevalence of vitamin D deficiency in heart failure””with some data suggesting the deficiency may be an independent predictor of mortality in heart failure patients. Classified as a vitamin, the highly hailed vitamin D actually functions as a steroid hormone. The hormone, per the Cenegenics-von Schwarz scientific review paper, is expressed in vascular smooth muscle cells and cardiac myocytes (heart muscle cells).

“Vitamin D is an iceberg. Beneath it is much more to discover about how to reduce oxidative stress through antioxidant therapy. In our investigation, we’ve put our emphasis on looking to improve not only cardiovascular disease, but also overall cardiovascular health through supplementation. The vitamin D story is now clear to most physicians who are recognizing it as an important pro-hormone that supports the concept that you can achieve a generalized effect and measurable results on health through a simple supplement,” Dr. Robert D. Willix, Jr. said.

Motorway
 
mmm, "worry" was a little exaggerated, I don't actually ever recall being constipated, all those spicy dishes and curries probably have me on the other side :)

GG, although I am aware that your comment was a light hearted one, but it does highlight the fact that there are many that have no desire to learn about nutrition and are quick to debunk or ridicule new findings.

Personally I find the subject fascinating, and if by chance, learning more about how our bodies work gives me an advantage, then that's a pretty good investment.


Mate, anyone who lives on the Eastern seaboard of Australia or in Perth and environs, who is not Aboriginal or homeless has a problem if they are Vitamin deficient.

The Great Barrier Reef is awash with the pee of the anxious and indolent gobbling Vitamins they do not need.

gg
 
Mate, anyone who lives on the Eastern seaboard of Australia or in Perth and environs, who is not Aboriginal or homeless has a problem if they are Vitamin deficient.

The Great Barrier Reef is awash with the pee of the anxious and indolent gobbling Vitamins they do not need.

gg

Yep, beginning to agree, but not being as learned as I could be, just learnin' some more.
 
75% Less Cancer Deaths with Vitamin D

If you are Vitamin D deficient anything will give you cancer ( In fact you can just get it without any outside cause . The communication between cells just breaks down )

This is the D stage of Dinomit cancer model
current screening only targets the O ( overgrowth ) stage



Roland I supplement because of all the benifits optimal levels Of D brings
and it is the only way to have stable year round levels

A healthy body uses 5000 iu a day ( D is used only once )
Fight a virus , a cancer , some other challenge eg I know a Psorasis Sufferer
The body will use more ( If it has it )

The research I have read
suggest 5000 iu a day safe and sensible

( but tests might show you need a lot more )

Here is a linK to the 7.30 report on curing multiple Sclerosis

http://www.overcomingmultiplesclerosis.org/Recovery-Program/Sunlight-and-Vitamin-D/

has some useful info on doses eg
There is evidence that optimal levels are really quite a bit higher24. The recommended daily allowance of vitamin D in Australia is 200IU. This amount of vitamin D is way too low. It is based on the amount required to prevent rickets.

It is equivalent to the amount of vitamin D your skin would make in 6 seconds of all over sun in Perth on a summer’s day. Vieth and others have shown that in sunny countries the vitamin D levels are at least 100-140nmol/L, and more like 135-225nmol/L, and that a level of 200nmol/L may actually be optimal.25 Others have suggested a level as high as 250nmol/L may be optimal.26

To achieve a level of 100nmol/L requires daily intake of about 4 000IU of vitamin D for people who are not getting any sun. To get to 140nmol/L needs about 10 000IU a day in the absence of sunlight. It has been shown that average healthy men’s bodies use about 3 000 to 5 000IU a day.5

It is not possible to get toxicity from vitamin D if it all comes from the sun. Only supplements can potentially produce toxic levels. The only published toxicity however is from supplements of 40 000IU a day.23

Roland the info you posted is only targeting bone health
Without bones you die so does the species ( Dinosaurs went extinct from Vit D deficiency )

Every bit of D you have in your body is prioritized to bone health
it takes the least amount to acheive this..
Only when this is optimal does D get used to fight cancer, viruses
Maintain other aspects of health

People I have known who have tested are all low
even on 2000 iu a day

the body does not reliably begin storing cholecalciferol in fat and muscle tissue until 25(OH)D levels get above 50 ng/ml (125 nmol/L). The average person starts to store cholecalciferol at 40 ng/ml (100 nmol/L), but at 50 ng/ml (125 nmol/L) virtually everyone begins to store it for future use.

That is, at levels below 50 ng/ml (125 nmol/L), the body uses up vitamin D as fast as you can make it, or take it, indicating chronic substrate starvation””not a good thing. 25(OH)D levels should be between 50–80 ng/ml (125–200 nmol/L), year-round.

I do not think it feasible to get to these levels without supplements
Unless you go live in the Tropics

Our winters will beat you
and if your levels drop
The Sun will then burn you

Motorway
 
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Mate, anyone who lives on the Eastern seaboard of Australia or in Perth and environs, who is not Aboriginal or homeless has a problem if they are Vitamin deficient.

The Great Barrier Reef is awash with the pee of the anxious and indolent gobbling Vitamins they do not need.

gg

Agree with you GG
Most supplements do more HARM than GOOD..

But Vitamin D is different
Both for what it does
and what we have done
with our modern life styles

Motorway
 
Motorway - you do mention the growing incidence of other diseases. Everyone has to die from something, and something has to be the #1 killer. With our ability to keep people alive longer, some of the later age diseases/conditions are now showing up in greater numbers. So this must be kept in mind.

However I agree (as posted in the Aspirin thread) with you re Vit D, and a female friend of ours was diagnosed an deficient - despite living in WA and working outdoors. I tend to think of getting a dose of sun like drinking alcohol. Binge drinking isn't good for your liver (body) and the same goes with the sun.

Incidentally you may be interested in an article re calcium supplementation without Vit D and heart risk.
http://www.theheart.org/article/1108009.do

and the following re Vit D and sunshine
http://www.lakelandecho.co.uk/nhshealth/Sun-and-vitamin-D-advice.6665055.jp

Off I go to get some Vit D.
Cheers
 
So what symptems would a person low in vitamin D show?

Maybe not a lot until the wheels fall off

Vitamin D allows the intelligence in the DNA Library inside each cell to be unlocked
(It has only been recently been realized what the entire Blueprint of the genome is doing inside each and every cell )

So with optimal Vitamin D , Everything works as and when it should

Ie insulin , immune system , blood pressure , brain , mood , calcium /bones
Heart , Muscle Strength etc

You name it... You are a living system with intelligence rife..cells communicating with each other ... Command and control systems all in place

Ready to meet any challenge..

Ok low vitamin D is like deciding to never check the oil air water or ever service
your car But just drive ( and with your eyes shut ) and throw out the manual...

For a while nothing will seem to happen
Until ..Something breaks down

And then maybe your dead
and in between you just do not feel well with aches and pains etc


johenmo
As far as dying, remember, everyone who takes Vitamin D will die. It's simply a question of when. What we hope, even expect, is vitamin D will square off the mortality curve. Now, people start dying from the diseases of civilization in their forties, struck down by heart disease, cancer, etc. Premature deaths accelerates in the 50s and are in full swing by the 60s.

That is, the mortality curve slops downward, beginning in the late 40s, people succumbing to the diseases of civilization. Perhaps vitamin D will allow people to live normal lives until they reach their 90s–100s, when we will all suddenly drop dead of old age!

Also most official recommendations are conservative still based on outdated models
The Understanding of Vitamin D is only very new eg what I have said above

Even recommendations For osteoporsis are too low ( SAILS for you ) ( still based on Rickets model )

in the very large population-based NHANES analysis, bone density increased with higher 25(OH)D levels far beyond 50 nmol/l in younger and older adults suggesting that the IOM threshold recommendation is too low for optimal bone health in adults[4]. In contrast to the IOM report, the IOF recommended in their 2010 position paper on vitamin D a threshold of 75 nmol/l for optimal fall and fracture reduction

And that is still just focusing on Bone Health..

This is important ... The old model saw Vitamin D just involved with Bones
BUT only 15% is for bones .. 85% is used by all the other cells in the body when they
need to do something intelligent.. eg A Heart Beating


See the Plate of the old scheme D for calcium/bones
Second is recent understanding Given optimal D
85% is for all the other cells and processes

ONLY 15% for bones

It only seemed that it was all for Bones
Because people were deficient and
Bones is where it all goes until there is optimal levels..

Calcitriol Made in KidneysThe first pathway leads to the kidney, where calcidiol is turned into calcitriol. Calcitriol is a potent steroid hormone, in fact, it is the most potent steroid hormone in the human body. A steroid hormone is simply any molecule in the body that is made from cholesterol and that acts to turn your genes on and off. They are always important to health, always need to be handled with care, and are often quite potent.

Calcitriol made by the kidney circulates in the blood to maintain your blood calcium levels. Calcium is vital to the function of the cells in the body, without enough calcitriol in the blood calcium levels will fall and illness will set in.

Therefore, the first priority for calcidiol is to go to the kidney where it makes enough calcitriol to secrete into the blood in order to regulate serum calcium.

The second vitamin D pathway leads to your tissues and that is where all the action is. All of the amazing health benefits of vitamin D discovered in the last 10 years are from vitamin D going down the second pathway. If any calcidiol is left over””that is, if your tank is full and your kidneys are getting all the calcidiol they need to maintain serum calcium””then calcidiol is able to take another pathway, one that leads directly to the cells.

This path is only now being fully understood and is causing excitement all around the world, especially concerning cancer. These are the autocrine (inside cell) and paracrine (around the cell) functions of the vitamin D system.These functions are crucial to understanding why you should keep your vitamin D tank full.

If you only have a small amount of calcidiol in your blood, virtually all of it goes to your kidney, which then makes extra calcitriol to keep your serum calcium levels from falling. Almost no calcidiol gets to your tissues to make tissue calcitriol.

So one thing you could get without sufficient D is cancer
or maybe Diabetes or Heart Disease
or Depression or whatever breaks down first..

eg cancer

But when your tank is full, the left over calcidiol goes to the many cells in the body that are able to make their own calcitriol to fight cancer””and they do so with gusto! In fact, they appear to make as much calcitriol as they can. The more calcidiol they get, the more calcitriol they make.


Breaking a Hip is a terrible thing to happen when you are over 50

You need levels of D where there is no limit on cells ability to self regulate
The Threshold where all The Vitamin D Tanks are FULL

motorway
 

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Thank you for the info. The reason i asked the question is we live on the east coast and my wife recently had a blood test and was for the first time diagnosed with low vitamin D
She has worked in a large shopping centre for 4 years now, previously a lot more time was spent outdoors.
In this time she has experienced more colds and gets fatigued much more easily and has just come down with a bad dose of broncitis, symptoms we atributed to being in air condiyioning and getting older, interesting to read this info.
Thank you
 
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